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Found 1 hit Enz. Inhib. hit(s) with Target = 'Ileal sodium/bile acid cotransporter' and Ligand = 'BDBM50322475'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ileal sodium/bile acid cotransporter


(Homo sapiens (Human))		BDBM50322475
PNG
((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Show SMILES C[C@H](CCC(=O)N[C@@H](CCC(=O)Nc1ccc(cc1)C(F)(F)F)C(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |r|
Show InChI InChI=1S/C36H51F3N2O6/c1-20(4-12-31(45)41-28(33(46)47)11-13-30(44)40-23-7-5-21(6-8-23)36(37,38)39)25-9-10-26-32-27(15-17-35(25,26)3)34(2)16-14-24(42)18-22(34)19-29(32)43/h5-8,20,22,24-29,32,42-43H,4,9-19H2,1-3H3,(H,40,44)(H,41,45)(H,46,47)/t20-,22-,24-,25-,26+,27+,28+,29-,32+,34+,35-/m1/s1
KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.02E+3n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation counting

J Med Chem 53: 4749-60 (2010)


Article DOI: 10.1021/jm1003683
BindingDB Entry DOI: 10.7270/Q2H70G0G
More data for this
Ligand-Target Pair