Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ileal sodium/bile acid cotransporter' and Ligand = 'BDBM50459098'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ileal sodium/bile acid cotransporter (Mus musculus)	BDBM50459098 (CHEMBL4205214) Show SMILES Clc1ccc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)c1 |r| Show InChI InChI=1S/C22H23Cl2N3OS/c23-16-5-8-18(24)15(11-16)12-25-14-29-13-21(25)22(28)27-10-9-26(17-6-7-17)19-3-1-2-4-20(19)27/h1-5,8,11,17,21H,6-7,9-10,12-14H2/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ardelyx, Inc. Curated by ChEMBL					Assay Description Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptake				J Med Chem 61: 7589-7613 (2018) Article DOI: 10.1021/acs.jmedchem.8b00308 BindingDB Entry DOI: 10.7270/Q2B56NCH
					More data for this Ligand-Target Pair
Ileal sodium/bile acid cotransporter (Homo sapiens (Human))	BDBM50459098 (CHEMBL4205214) Show SMILES Clc1ccc(Cl)c(CN2CSC[C@H]2C(=O)N2CCN(C3CC3)c3ccccc23)c1 |r| Show InChI InChI=1S/C22H23Cl2N3OS/c23-16-5-8-18(24)15(11-16)12-25-14-29-13-21(25)22(28)27-10-9-26(17-6-7-17)19-3-1-2-4-20(19)27/h1-5,8,11,17,21H,6-7,9-10,12-14H2/t21-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ardelyx, Inc. Curated by ChEMBL					Assay Description Inhibition of human IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptake				J Med Chem 61: 7589-7613 (2018) Article DOI: 10.1021/acs.jmedchem.8b00308 BindingDB Entry DOI: 10.7270/Q2B56NCH
					More data for this Ligand-Target Pair