Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM423348'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM423348 (US10501458, Compound 1021) Show SMILES CC1(C)CN(CCN1C(O)=O)c1cc(Br)cc2cncn12 Show InChI InChI=1S/C14H17BrN4O2/c1-14(2)8-17(3-4-19(14)13(20)21)12-6-10(15)5-11-7-16-9-18(11)12/h5-7,9H,3-4,8H2,1-2H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Iomet Pharma Ltd.; Merck Sharp & Dohme Corp. US Patent					Assay Description Compounds to be tested were serially diluted in ten 3-fold steps in DMSO starting from 10 mM DMSO stocks. Compound dilutions or DMSO alone were then ...				US Patent US10501458 (2019) BindingDB Entry DOI: 10.7270/Q26T0Q1W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM423348 (US10501458, Compound 1021) Show SMILES CC1(C)CN(CCN1C(O)=O)c1cc(Br)cc2cncn12 Show InChI InChI=1S/C14H17BrN4O2/c1-14(2)8-17(3-4-19(14)13(20)21)12-6-10(15)5-11-7-16-9-18(11)12/h5-7,9H,3-4,8H2,1-2H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	n/a	n/a
Iomet Pharma Ltd.; Merck Sharp & Dohme Corp. US Patent					Assay Description Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...				US Patent US10501458 (2019) BindingDB Entry DOI: 10.7270/Q26T0Q1W
					More data for this Ligand-Target Pair