Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM494729'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494729 (N-ethyl-2-((4-(N-(6-fluoro-2,3- dihydro-1H-inden-1...) Show SMILES CCNC(=O)CNc1nonc1\C(NC1CCc2ccc(F)cc12)=N\O Show InChI InChI=1S/C16H19FN6O3/c1-2-18-13(24)8-19-15-14(22-26-23-15)16(21-25)20-12-6-4-9-3-5-10(17)7-11(9)12/h3,5,7,12,25H,2,4,6,8H2,1H3,(H,18,24)(H,19,23)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51.4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021) BindingDB Entry DOI: 10.7270/Q25T3PKG
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