Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM494768'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494768 (N-(4-fluorobicyclo[4.2.0]octa- 1(6),2,4-trien-7-yl...) Show SMILES NC(=O)NCCNc1nonc1\C(NC1Cc2ccc(F)cc12)=N\O Show InChI InChI=1S/C14H16FN7O3/c15-8-2-1-7-5-10(9(7)6-8)19-13(20-24)11-12(22-25-21-11)17-3-4-18-14(16)23/h1-2,6,10,24H,3-5H2,(H,17,22)(H,19,20)(H3,16,18,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021) BindingDB Entry DOI: 10.7270/Q25T3PKG
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