Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 2' and Ligand = 'BDBM50514034'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 2 (Homo sapiens (Human))	BDBM50514034 (CHEMBL4588805) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(CN4CCOCC4)cc3c(=O)n-21 Show InChI InChI=1S/C20H16FN3O3/c21-13-2-4-17-15(10-13)18(25)19-22-16-3-1-12(9-14(16)20(26)24(17)19)11-23-5-7-27-8-6-23/h1-4,9-10H,5-8,11H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Uncompetitive inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition co...				J Med Chem 62: 9161-9174 (2019) Article DOI: 10.1021/acs.jmedchem.9b01079 BindingDB Entry DOI: 10.7270/Q27W6GJ0
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Homo sapiens (Human))	BDBM50514034 (CHEMBL4588805) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(CN4CCOCC4)cc3c(=O)n-21 Show InChI InChI=1S/C20H16FN3O3/c21-13-2-4-17-15(10-13)18(25)19-22-16-3-1-12(9-14(16)20(26)24(17)19)11-23-5-7-27-8-6-23/h1-4,9-10H,5-8,11H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of human IDO2 transfected in human U87MG cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated wi...				J Med Chem 62: 9161-9174 (2019) Article DOI: 10.1021/acs.jmedchem.9b01079 BindingDB Entry DOI: 10.7270/Q27W6GJ0
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Homo sapiens (Human))	BDBM50514034 (CHEMBL4588805) Show SMILES Fc1ccc-2c(c1)C(=O)c1nc3ccc(CN4CCOCC4)cc3c(=O)n-21 Show InChI InChI=1S/C20H16FN3O3/c21-13-2-4-17-15(10-13)18(25)19-22-16-3-1-12(9-14(16)20(26)24(17)19)11-23-5-7-27-8-6-23/h1-4,9-10H,5-8,11H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in conversion of ...				J Med Chem 62: 9161-9174 (2019) Article DOI: 10.1021/acs.jmedchem.9b01079 BindingDB Entry DOI: 10.7270/Q27W6GJ0
					More data for this Ligand-Target Pair