Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM142751'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM142751 (US8937193, 6c) Show SMILES Cc1c(-c2c(C)c(=O)c3c(CC4CCCC4)c(O)c(O)cc3c2=O)c(=O)c2cc(O)c(O)c(CC3CCCC3)c2c1=O |(-.65,-2.45,;-1.98,-1.68,;-1.98,-.14,;-.65,.63,;-.65,2.17,;-1.98,2.94,;.69,2.94,;.69,4.48,;2.02,2.17,;3.36,2.94,;3.36,4.48,;4.69,5.25,;5.01,6.75,;6.54,6.91,;7.17,5.51,;6.02,4.48,;4.69,2.17,;6.02,2.94,;4.69,.63,;6.02,-.14,;3.36,-.14,;2.02,.63,;.69,-.2,;.69,-1.74,;-3.31,.68,;-3.31,2.22,;-4.65,-.14,;-5.98,.63,;-7.31,-.14,;-8.65,.63,;-7.31,-1.68,;-8.65,-2.45,;-5.98,-2.45,;-5.98,-3.99,;-7.31,-4.76,;-8.56,-3.86,;-9.81,-4.76,;-9.33,-6.23,;-7.79,-6.23,;-4.65,-1.68,;-3.31,-2.45,;-3.31,-3.99,)| Show InChI InChI=1S/C34H34O8/c1-15-25(33(41)21-13-23(35)31(39)19(27(21)29(15)37)11-17-7-3-4-8-17)26-16(2)30(38)28-20(12-18-9-5-6-10-18)32(40)24(36)14-22(28)34(26)42/h13-14,17-18,35-36,39-40H,3-12H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	25
Sanford-Burnham Medical Research Institute US Patent					Assay Description A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...				US Patent US8937193 (2015) BindingDB Entry DOI: 10.7270/Q20C4TG4
					More data for this Ligand-Target Pair