Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM38047'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM38047 (3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-(naph...) Show SMILES Cc1cc(OCCCc2c(oc3ccccc23)C(=O)NS(=O)(=O)c2cccc3ccccc23)cc(C)c1Cl Show InChI InChI=1S/C19H18FN3O3/c1-11-9-15-17(19(24)23(11)7-8-25-2)16(13(10-21)18(22)26-15)12-5-3-4-6-14(12)20/h3-6,9,13,16,22H,7-8H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...				US Patent US10093646 (2018) BindingDB Entry DOI: 10.7270/Q29P33PN
					More data for this Ligand-Target Pair