Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50127759'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50127759 (CHEMBL3628078) Show SMILES OC(=O)c1ccc(COc2ccc(\C=C3/SC(=S)N(C3=O)c3ccc(I)cc3)cc2)cc1 Show InChI InChI=1S/C24H16INO4S2/c25-18-7-9-19(10-8-18)26-22(27)21(32-24(26)31)13-15-3-11-20(12-4-15)30-14-16-1-5-17(6-2-16)23(28)29/h1-13H,14H2,(H,28,29)/b21-13-	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Mcl-1 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem Lett 25: 5265-9 (2015) Article DOI: 10.1016/j.bmcl.2015.09.051 BindingDB Entry DOI: 10.7270/Q2RB76DD
					More data for this Ligand-Target Pair