Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50176886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50176886 (CHEMBL3813743) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)c(F)c2)c(OC)c1OC Show InChI InChI=1S/C18H17FO5/c1-22-16-9-6-12(17(23-2)18(16)24-3)14(20)7-4-11-5-8-15(21)13(19)10-11/h4-10,21H,1-3H3/b7-4+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to PEST and transmembrane regions lacking N-terminal His6/MBP-tagged human MCl1 (172 to 327 residues) expressed in Escherichia coli ...				J Med Chem 59: 4152-70 (2016) Article DOI: 10.1021/acs.jmedchem.5b00150 BindingDB Entry DOI: 10.7270/Q2TX3H9R
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