Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50316815'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50316815 ((1R,3S,4R,8S,10R,11S,14R)-4-methoxy-10,11-dimethyl...) Show SMILES CCC(C)CC(C)CC(O)(CO)C(=O)O[C@@H]1CC[C@H](C)[C@@]2(C)C[C@H]3C(=C)CO[C@@]3(OC)[C@H]3O[C@@]123 |r| Show InChI InChI=1S/C27H44O7/c1-8-16(2)11-17(3)12-25(30,15-28)23(29)33-21-10-9-19(5)24(6)13-20-18(4)14-32-27(20,31-7)22-26(21,24)34-22/h16-17,19-22,28,30H,4,8-15H2,1-3,5-7H3/t16?,17?,19-,20-,21+,22-,24+,25?,26+,27+/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California-San Diego Curated by ChEMBL					Assay Description Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assay				J Nat Prod 73: 998-1001 (2010) Article DOI: 10.1021/np1000889 BindingDB Entry DOI: 10.7270/Q2RR1ZCX
					More data for this Ligand-Target Pair