Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50441886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50441886 (CHEMBL2436887) Show SMILES Oc1cc(C(=O)NCc2ccccc2)c(NC(=O)c2ccccc2)c(O)c1O Show InChI InChI=1S/C21H18N2O5/c24-16-11-15(21(28)22-12-13-7-3-1-4-8-13)17(19(26)18(16)25)23-20(27)14-9-5-2-6-10-14/h1-11,24-26H,12H2,(H,22,28)(H,23,27)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Displacement of FAM-Bid BH3 peptide from recombinant Mcl-1 (unknown origin) expressed in Escherichia coli BL21 after 10 mins by fluorescence polariza...				Eur J Med Chem 69: 711-8 (2013) Article DOI: 10.1016/j.ejmech.2013.09.030 BindingDB Entry DOI: 10.7270/Q2348MT5
					More data for this Ligand-Target Pair