Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM26090'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM26090 (5-acetylenyl-3-thiophenecarboxamide, 1n | N-(3-{2-...) Show SMILES NC(=O)Nc1sc(cc1C(N)=O)C#Cc1cccc(NC(=O)c2cccnc2)c1 Show InChI InChI=1S/C20H15N5O3S/c21-17(26)16-10-15(29-19(16)25-20(22)28)7-6-12-3-1-5-14(9-12)24-18(27)13-4-2-8-23-11-13/h1-5,8-11H,(H2,21,26)(H,24,27)(H3,22,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	557	n/a	n/a	n/a	n/a	7.6	25
Pfizer					Assay Description The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...				Bioorg Med Chem Lett 15: 2870-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.090 BindingDB Entry DOI: 10.7270/Q2T72FRG
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