Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM50149824'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50149824 (2-Amino-4-(1-amino-2-methyl-propyl)-6-(2-hydroxy-p...) Show SMILES CC(C)C(N)c1cc(nc(N)c1C#N)-c1ccccc1O Show InChI InChI=1S/C16H18N4O/c1-9(2)15(18)11-7-13(20-16(19)12(11)8-17)10-5-3-4-6-14(10)21/h3-7,9,15,21H,18H2,1-2H3,(H2,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 619-0216 Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human I-kappa-B-kinase beta				Bioorg Med Chem Lett 14: 4013-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.040 BindingDB Entry DOI: 10.7270/Q2PC31VC
					More data for this Ligand-Target Pair