Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum) | BDBM50398417 (CHEMBL2178652) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Brandeis University Curated by ChEMBL | Assay Description Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | ACS Med Chem Lett 5: 846-50 (2014) Article DOI: 10.1021/ml500203p BindingDB Entry DOI: 10.7270/Q23J3FN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum) | BDBM50398417 (CHEMBL2178652) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Brandeis University Curated by ChEMBL | Assay Description Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce... | J Med Chem 55: 7759-71 (2012) Article DOI: 10.1021/jm3007917 BindingDB Entry DOI: 10.7270/Q2GM88GS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase (Bacillus anthracis) | BDBM50398417 (CHEMBL2178652) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Brandeis University Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometry | ACS Med Chem Lett 5: 846-50 (2014) Article DOI: 10.1021/ml500203p BindingDB Entry DOI: 10.7270/Q23J3FN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum) | BDBM50398417 (CHEMBL2178652) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Brandeis University Curated by ChEMBL | Assay Description Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f... | J Med Chem 55: 7759-71 (2012) Article DOI: 10.1021/jm3007917 BindingDB Entry DOI: 10.7270/Q2GM88GS | |||||||||||
More data for this Ligand-Target Pair |