Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM248130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM248130 (IMPDH II inhibitor, 49) Show SMILES COc1cc(N\C(Nc2cccc(Cc3nnn(C)n3)c2)=N\C#N)ccc1C#N Show InChI InChI=1S/C19H17N9O/c1-28-26-18(25-27-28)9-13-4-3-5-15(8-13)23-19(22-12-21)24-16-7-6-14(11-20)17(10-16)29-2/h3-8,10H,9H2,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<3.00E+4	n/a	n/a	n/a	n/a	8.0	37
Nycomed					Assay Description The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...				J Enzyme Inhib Med Chem 29: 408-19 (2014) Article DOI: 10.3109/14756366.2013.793184 BindingDB Entry DOI: 10.7270/Q28P5ZDV
					More data for this Ligand-Target Pair