Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM50133711'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50133711 (CHEMBL333901 | N-{3-[2-(3-Cyano-1-methyl-1H-indol-...) Show SMILES Cn1cc(C#N)c2ccc(Nc3ncc(o3)-c3cccc(CNC(=O)c4ccccc4)c3)cc12 Show InChI InChI=1S/C27H21N5O2/c1-32-17-21(14-28)23-11-10-22(13-24(23)32)31-27-30-16-25(34-27)20-9-5-6-18(12-20)15-29-26(33)19-7-3-2-4-8-19/h2-13,16-17H,15H2,1H3,(H,29,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme				Bioorg Med Chem Lett 13: 3557-60 (2003) BindingDB Entry DOI: 10.7270/Q2J67G94
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