Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM50133725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50133725 (CHEMBL119408 | Naphthalene-2-carboxylic acid 3-[2-...) Show SMILES Cn1cc(C#N)c2ccc(Nc3ncc(o3)-c3cccc(CNC(=O)c4ccc5ccccc5c4)c3)cc12 Show InChI InChI=1S/C31H23N5O2/c1-36-19-25(16-32)27-12-11-26(15-28(27)36)35-31-34-18-29(38-31)23-8-4-5-20(13-23)17-33-30(37)24-10-9-21-6-2-3-7-22(21)14-24/h2-15,18-19H,17H2,1H3,(H,33,37)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme				Bioorg Med Chem Lett 13: 3557-60 (2003) BindingDB Entry DOI: 10.7270/Q2J67G94
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