Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM50133729'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50133729 (1-(4-Cyano-3-methoxy-phenyl)-3-m-tolyl-urea | CHEM...) Show SMILES COc1cc(NC(=O)Nc2cccc(C)c2)ccc1C#N Show InChI InChI=1S/C16H15N3O2/c1-11-4-3-5-13(8-11)18-16(20)19-14-7-6-12(10-17)15(9-14)21-2/h3-9H,1-2H3,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme				Bioorg Med Chem Lett 13: 3557-60 (2003) BindingDB Entry DOI: 10.7270/Q2J67G94
					More data for this Ligand-Target Pair