Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin receptor' and Ligand = 'BDBM50092144'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50092144 (2,5-Dihydroxy-3-(1H-indol-3-yl)-6-(7-methyl-1H-ind...) Show SMILES Cc1cccc2c(c[nH]c12)C1C(=O)C(=O)C(c2c[nH]c3ccccc23)C(=O)C1=O |(.75,-7.3,;1.22,-5.83,;.15,-4.69,;.61,-3.18,;2.15,-2.85,;3.2,-4,;4.72,-4,;5.21,-5.44,;3.97,-6.37,;2.74,-5.49,;6.05,-3.23,;6.05,-1.69,;4.72,-.92,;7.38,-.91,;7.38,.63,;8.71,-1.69,;10.04,-.92,;10.22,.65,;11.72,.96,;12.47,-.4,;13.96,-.72,;14.43,-2.18,;13.39,-3.32,;11.88,-2.99,;11.43,-1.52,;8.71,-3.23,;10.04,-4,;7.38,-3.99,;7.38,-5.53,)| Show InChI InChI=1S/C23H16N2O4/c1-11-5-4-7-13-15(10-25-19(11)13)18-22(28)20(26)17(21(27)23(18)29)14-9-24-16-8-3-2-6-12(14)16/h2-10,17-18,24-25H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activation of human insulin receptor tyrosine kinase (IRTK)				J Med Chem 43: 3487-94 (2000) BindingDB Entry DOI: 10.7270/Q2NV9HHG
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