Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin receptor' and Ligand = 'BDBM50253176'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Mus musculus)	BDBM50253176 (4-{7-[({7-[(4-carboxyphenyl)sulfamoyl]naphthalen-2...) Show SMILES OC(=O)c1ccc(NS(=O)(=O)c2ccc3ccc(NC(=O)Nc4ccc5ccc(cc5c4)S(=O)(=O)Nc4ccc(cc4)C(O)=O)cc3c2)cc1 Show InChI InChI=1S/C35H26N4O9S2/c40-33(41)23-3-9-27(10-4-23)38-49(45,46)31-15-7-21-1-13-29(17-25(21)19-31)36-35(44)37-30-14-2-22-8-16-32(20-26(22)18-30)50(47,48)39-28-11-5-24(6-12-28)34(42)43/h1-20,38-39H,(H,40,41)(H,42,43)(H2,36,37,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.83E+5	n/a	n/a	n/a	n/a
Telik, Inc. Curated by ChEMBL					Assay Description Activation of insulin receptor tyrosine kinase in mouse 3T3-L1 cells assessed as increase in 2-deoxy-D-[14C]glucose transport in presence of insulin				J Med Chem 51: 6173-87 (2008) Article DOI: 10.1021/jm800600v BindingDB Entry DOI: 10.7270/Q2ZG6T5K
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