Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin receptor' and Ligand = 'BDBM50420958'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50420958 (CHEMBL2088094) Show SMILES CCCc1cc(Nc2nc(NCc3cc(C)no3)ncc2Br)[nH]n1 Show InChI InChI=1S/C15H18BrN7O/c1-3-4-10-6-13(22-21-10)19-14-12(16)8-18-15(20-14)17-7-11-5-9(2)23-24-11/h5-6,8H,3-4,7H2,1-2H3,(H3,17,18,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human INSR phosphorylation over expressed in CHOT cells after 60 mins by immunoblotting				J Med Chem 55: 5003-12 (2012) Article DOI: 10.1021/jm3004043 BindingDB Entry DOI: 10.7270/Q25X2B62
					More data for this Ligand-Target Pair