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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM106985'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM106985
PNG
(US8592579, 23)
Show SMILES CCOC(=O)c1ccc(NC(=O)[C@@H]2CCCN2c2nc(Nc3cc([nH]n3)C3CC3)c3cccn3n2)cc1 |r|
Show InChI InChI=1S/C26H28N8O3/c1-2-37-25(36)17-9-11-18(12-10-17)27-24(35)21-6-3-13-33(21)26-29-23(20-5-4-14-34(20)32-26)28-22-15-19(30-31-22)16-7-8-16/h4-5,9-12,14-16,21H,2-3,6-8,13H2,1H3,(H,27,35)(H2,28,29,30,31,32)/t21-/m0/s1
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MMDB

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Similars

US Patent
n/an/a 1.76E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Kinase assay using IGF1-receptor.


US Patent US8592579 (2013)


BindingDB Entry DOI: 10.7270/Q2SQ8Z12
More data for this
Ligand-Target Pair