Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM122626'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM122626 (US8735386, I-96) Show SMILES COc1cc(OCCN2CCCC2)ccc1Nc1ncc2C(C)Cc3nn(C)c(c3-c2n1)-c1ccccc1Cl |(-.13,-2.03,;-1.46,-1.26,;-1.46,.28,;-2.79,1.05,;-2.79,2.59,;-4.13,3.36,;-5.46,2.59,;-5.46,1.05,;-6.79,.28,;-8.26,.75,;-9.16,-.49,;-8.26,-1.74,;-6.79,-1.26,;-1.46,3.36,;-.13,2.59,;-.13,1.05,;1.21,.28,;2.54,1.05,;2.54,2.59,;3.88,3.36,;5.21,2.59,;6.54,3.36,;6.54,4.9,;7.88,2.59,;7.88,1.05,;9.02,.02,;8.39,-1.39,;9.16,-2.73,;6.86,-1.23,;6.54,.28,;5.21,1.05,;3.88,.28,;5.77,-2.32,;4.29,-1.92,;3.2,-3.01,;3.6,-4.5,;5.08,-4.9,;6.17,-3.81,;7.66,-4.21,)| Show InChI InChI=1S/C30H33ClN6O2/c1-19-16-25-27(29(36(2)35-25)21-8-4-5-9-23(21)31)28-22(19)18-32-30(34-28)33-24-11-10-20(17-26(24)38-3)39-15-14-37-12-6-7-13-37/h4-5,8-11,17-19H,6-7,12-16H2,1-3H3,(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...				US Patent US8735386 (2014) BindingDB Entry DOI: 10.7270/Q2C827Z0
					More data for this Ligand-Target Pair