Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM122697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM122697 (US8735386, I-167) Show SMILES COCCN1CCN(CCn2ccc(Nc3ncc4CCc5nn(C)c(c5-c4n3)-c3ccccc3)n2)CC1 Show InChI InChI=1S/C28H35N9O/c1-34-27(21-6-4-3-5-7-21)25-23(32-34)9-8-22-20-29-28(31-26(22)25)30-24-10-11-37(33-24)17-16-35-12-14-36(15-13-35)18-19-38-2/h3-7,10-11,20H,8-9,12-19H2,1-2H3,(H,29,30,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...				US Patent US8735386 (2014) BindingDB Entry DOI: 10.7270/Q2C827Z0
					More data for this Ligand-Target Pair