Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM122705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM122705 (US8735386, I-175) Show SMILES CN(C)C1CCN(CCn2ccc(Nc3ncc4CCc5nn(C)c(c5-c4n3)-c3ccccc3)n2)CC1 Show InChI InChI=1S/C28H35N9/c1-34(2)22-11-14-36(15-12-22)17-18-37-16-13-24(33-37)30-28-29-19-21-9-10-23-25(26(21)31-28)27(35(3)32-23)20-7-5-4-6-8-20/h4-8,13,16,19,22H,9-12,14-15,17-18H2,1-3H3,(H,29,30,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...				US Patent US8735386 (2014) BindingDB Entry DOI: 10.7270/Q2C827Z0
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