Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM122881'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM122881 (US8735386, III-43) Show SMILES COCCN1CCC(CC1)NC(=O)c1ccc(Nc2ncc3C(C)Cc4nn(C)c(c4-c3n2)-c2ccccc2Cl)c(OC)c1 |(-11.31,2.2,;-9.98,2.97,;-9.98,4.51,;-8.65,5.28,;-7.31,4.51,;-5.98,5.28,;-4.65,4.51,;-4.65,2.97,;-5.98,2.2,;-7.31,2.97,;-3.31,2.2,;-1.98,2.97,;-1.98,4.51,;-.64,2.2,;.69,2.97,;2.02,2.2,;2.02,.66,;3.36,-.11,;4.69,.66,;4.69,2.2,;6.02,2.97,;7.36,2.2,;8.69,2.97,;8.69,4.51,;10.03,2.2,;10.03,.66,;11.17,-.37,;10.54,-1.78,;11.31,-3.11,;9.01,-1.62,;8.69,-.11,;7.36,.66,;6.02,-.11,;7.92,-2.7,;6.44,-2.31,;5.35,-3.39,;5.75,-4.88,;7.23,-5.28,;8.32,-4.19,;9.81,-4.59,;.69,-.11,;.69,-1.65,;2.02,-2.42,;-.64,.66,)| Show InChI InChI=1S/C33H38ClN7O3/c1-20-17-27-29(31(40(2)39-27)23-7-5-6-8-25(23)34)30-24(20)19-35-33(38-30)37-26-10-9-21(18-28(26)44-4)32(42)36-22-11-13-41(14-12-22)15-16-43-3/h5-10,18-20,22H,11-17H2,1-4H3,(H,36,42)(H,35,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...				US Patent US8735386 (2014) BindingDB Entry DOI: 10.7270/Q2C827Z0
					More data for this Ligand-Target Pair