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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM15017'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM15017
PNG
(2-tert-Butyl 4-Ethyl 3-Ethyl-5-formyl-1-methyl-1H-...)
Show SMILES CCOC(=O)c1c(CC)c(C(=O)OC(C)(C)C)n(C)c1C=O
Show InChI InChI=1S/C16H23NO5/c1-7-10-12(14(19)21-8-2)11(9-18)17(6)13(10)15(20)22-16(3,4)5/h9H,7-8H2,1-6H3
PDB
MMDB

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Article
PubMed
n/an/a 4.30E+3n/an/an/an/a7.422



Merck Research Laboratories



Assay Description
The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...


Biochemistry 44: 9430-40 (2005)


Article DOI: 10.1021/bi0500628
BindingDB Entry DOI: 10.7270/Q2BV7DV5
More data for this
Ligand-Target Pair