Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM1779'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM1779 (CHEMBL392106 | US8481733, Comparator 2) Show SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4)c3)c12)C1CCC1 Show InChI InChI=1S/C23H22N4O/c24-22-21-20(26-23(17-8-4-9-17)27(21)13-12-25-22)18-10-5-11-19(14-18)28-15-16-6-2-1-3-7-16/h1-3,5-7,10-14,17H,4,8-9,15H2,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	606	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-IGF1R activity				Bioorg Med Chem Lett 17: 1091-7 (2007) Article DOI: 10.1016/j.bmcl.2006.11.016 BindingDB Entry DOI: 10.7270/Q2QZ29MB
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM1779 (CHEMBL392106 | US8481733, Comparator 2) Show SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4)c3)c12)C1CCC1 Show InChI InChI=1S/C23H22N4O/c24-22-21-20(26-23(17-8-4-9-17)27(21)13-12-25-22)18-10-5-11-19(14-18)28-15-16-6-2-1-3-7-16/h1-3,5-7,10-14,17H,4,8-9,15H2,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cells				Bioorg Med Chem 16: 1359-75 (2008) Article DOI: 10.1016/j.bmc.2007.10.061 BindingDB Entry DOI: 10.7270/Q2WH2QVH
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM1779 (CHEMBL392106 | US8481733, Comparator 2) Show SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4)c3)c12)C1CCC1 Show InChI InChI=1S/C23H22N4O/c24-22-21-20(26-23(17-8-4-9-17)27(21)13-12-25-22)18-10-5-11-19(14-18)28-15-16-6-2-1-3-7-16/h1-3,5-7,10-14,17H,4,8-9,15H2,(H2,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cells				Bioorg Med Chem Lett 17: 1091-7 (2007) Article DOI: 10.1016/j.bmcl.2006.11.016 BindingDB Entry DOI: 10.7270/Q2QZ29MB
					More data for this Ligand-Target Pair