Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 35.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre Universitaire Curated by ChEMBL | Assay Description Inhibition of IGF1R | Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in baculovirus-SF21 cell system preincubated for 5 mins by time... | Bioorg Med Chem Lett 21: 2224-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.003 BindingDB Entry DOI: 10.7270/Q2CC11PK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in baculovirus-SF21 cell system preincubated for 30 mins by tim... | Bioorg Med Chem Lett 21: 2224-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.003 BindingDB Entry DOI: 10.7270/Q2CC11PK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in baculovirus-SF21 cell system preincubated for 60 mins by tim... | Bioorg Med Chem Lett 21: 2224-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.003 BindingDB Entry DOI: 10.7270/Q2CC11PK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-aventis Curated by ChEMBL | Assay Description Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in baculovirus-SF21 cell system preincubated for 10 mins by tim... | Bioorg Med Chem Lett 21: 2224-8 (2011) Article DOI: 10.1016/j.bmcl.2011.03.003 BindingDB Entry DOI: 10.7270/Q2CC11PK | |||||||||||
More data for this Ligand-Target Pair |