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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50071022'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50071022
PNG
(CHEMBL3409732)
Show SMILES CC(C)(C)c1cc(Nc2nc(nc3CCCc23)N2CCCCC2)n[nH]1
Show InChI InChI=1S/C19H28N6/c1-19(2,3)15-12-16(24-23-15)21-17-13-8-7-9-14(13)20-18(22-17)25-10-5-4-6-11-25/h12H,4-11H2,1-3H3,(H2,20,21,22,23,24)
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MMDB

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Article
PubMed
n/an/a 251n/an/an/an/an/an/a



Piramal Enterprises Limited

Curated by ChEMBL


Assay Description
Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...


Eur J Med Chem 92: 246-56 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.053
BindingDB Entry DOI: 10.7270/Q2639RFV
More data for this
Ligand-Target Pair