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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50071026'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50071026
PNG
(CHEMBL3409728)
Show SMILES C1CC1c1cc(Nc2nc(nc3CCCc23)-c2ccccc2)n[nH]1
Show InChI InChI=1S/C19H19N5/c1-2-5-13(6-3-1)18-20-15-8-4-7-14(15)19(22-18)21-17-11-16(23-24-17)12-9-10-12/h1-3,5-6,11-12H,4,7-10H2,(H2,20,21,22,23,24)
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MMDB

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Article
PubMed
n/an/a 97n/an/an/an/an/an/a



Piramal Enterprises Limited

Curated by ChEMBL


Assay Description
Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...


Eur J Med Chem 92: 246-56 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.053
BindingDB Entry DOI: 10.7270/Q2639RFV
More data for this
Ligand-Target Pair