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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50071028'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50071028
PNG
(CHEMBL3409726)
Show SMILES CC1CCN(CC1)c1nc2CCCc2c(Nc2cc([nH]n2)-c2ccccc2)n1
Show InChI InChI=1S/C22H26N6/c1-15-10-12-28(13-11-15)22-23-18-9-5-8-17(18)21(25-22)24-20-14-19(26-27-20)16-6-3-2-4-7-16/h2-4,6-7,14-15H,5,8-13H2,1H3,(H2,23,24,25,26,27)
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Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Piramal Enterprises Limited

Curated by ChEMBL


Assay Description
Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...


Eur J Med Chem 92: 246-56 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.053
BindingDB Entry DOI: 10.7270/Q2639RFV
More data for this
Ligand-Target Pair