Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50375337'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50375337 (CHEMBL413828) Show SMILES CN(C)C[C@H]1C[C@H](C1)c1nc(-c2ccc3ccc(nc3c2)-c2ccccc2)c2c(N)nccn12 |wU:6.8,4.3,(25.03,-21.69,;24.56,-20.23,;23.05,-19.91,;25.59,-19.08,;25.11,-17.62,;23.74,-16.92,;24.43,-15.55,;25.81,-16.24,;23.95,-14.09,;24.86,-12.83,;23.95,-11.57,;24.73,-10.25,;23.97,-8.92,;24.73,-7.59,;26.28,-7.59,;27.05,-6.26,;28.59,-6.27,;29.37,-7.61,;28.59,-8.94,;27.05,-8.94,;26.27,-10.26,;30.91,-7.61,;31.68,-8.95,;33.22,-8.95,;33.99,-7.62,;33.21,-6.28,;31.68,-6.29,;22.48,-12.05,;21.14,-11.29,;21.13,-9.75,;19.81,-12.06,;19.81,-13.61,;21.14,-14.38,;22.48,-13.61,)| Show InChI InChI=1S/C28H28N6/c1-33(2)17-18-14-22(15-18)28-32-25(26-27(29)30-12-13-34(26)28)21-9-8-20-10-11-23(31-24(20)16-21)19-6-4-3-5-7-19/h3-13,16,18,22H,14-15,17H2,1-2H3,(H2,29,30)/t18-,22+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cells				Bioorg Med Chem 16: 1359-75 (2008) Article DOI: 10.1016/j.bmc.2007.10.061 BindingDB Entry DOI: 10.7270/Q2WH2QVH
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