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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50378023'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50378023
PNG
(CHEMBL1964271)
Show SMILES COc1cc(ccc1Nc1nc(N2CCc3ccccc23)c2cc[nH]c2n1)N1CCN(CC1)C(C)C
Show InChI InChI=1S/C28H33N7O/c1-19(2)33-14-16-34(17-15-33)21-8-9-23(25(18-21)36-3)30-28-31-26-22(10-12-29-26)27(32-28)35-13-11-20-6-4-5-7-24(20)35/h4-10,12,18-19H,11,13-17H2,1-3H3,(H2,29,30,31,32)
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PC cid
PC sid
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Article
PubMed
n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of IGF1R


Bioorg Med Chem Lett 19: 373-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.065
BindingDB Entry DOI: 10.7270/Q2F190PC
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50378023
PNG
(CHEMBL1964271)
Show SMILES COc1cc(ccc1Nc1nc(N2CCc3ccccc23)c2cc[nH]c2n1)N1CCN(CC1)C(C)C
Show InChI InChI=1S/C28H33N7O/c1-19(2)33-14-16-34(17-15-33)21-8-9-23(25(18-21)36-3)30-28-31-26-22(10-12-29-26)27(32-28)35-13-11-20-6-4-5-7-24(20)35/h4-10,12,18-19H,11,13-17H2,1-3H3,(H2,29,30,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.77E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of IGF1R phosphorylation by cellular assay


Bioorg Med Chem Lett 19: 373-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.065
BindingDB Entry DOI: 10.7270/Q2F190PC
More data for this
Ligand-Target Pair