BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM50187188'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50187188
PNG
(CHEMBL209641 | methyl 3-(7-(4-fluorobenzyl)-9-hydr...)
Show SMILES COC(=O)CCSC1N(Cc2ccc(F)cc2)C(=O)c2c1c(OC)c1cccnc1c2O
Show InChI InChI=1S/C23H21FN2O5S/c1-30-16(27)9-11-32-23-18-17(20(28)19-15(21(18)31-2)4-3-10-25-19)22(29)26(23)12-13-5-7-14(24)8-6-13/h3-8,10,23,28H,9,11-12H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Gilead Sciences

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity in MT4 cell line

Bioorg Med Chem Lett 16: 4031-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.008
BindingDB Entry DOI: 10.7270/Q2QR4WRV
More data for this
Ligand-Target Pair