Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrase (Human immunodeficiency virus 1) | BDBM50246665 (2-(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydr...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of HIV1 His6-tagged integrase-human GST tagged LEDGF/p75 (373-442 residues) interaction after 30 mins by AlphaScreen assay | J Med Chem 55: 10108-17 (2012) Article DOI: 10.1021/jm301226a BindingDB Entry DOI: 10.7270/Q2028VFH | |||||||||||
More data for this Ligand-Target Pair |