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Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM50485874'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50485874
PNG
(CHEMBL2171671)
Show SMILES OC(=O)c1[nH]cc(C(=O)NCc2ccc(F)cc2)c(=O)c1O
Show InChI InChI=1S/C14H11FN2O5/c15-8-3-1-7(2-4-8)5-17-13(20)9-6-16-10(14(21)22)12(19)11(9)18/h1-4,6,19H,5H2,(H,16,18)(H,17,20)(H,21,22)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...

J Med Chem 55: 8735-44 (2012)


Article DOI: 10.1021/jm3010459
BindingDB Entry DOI: 10.7270/Q27M0BTW
More data for this
Ligand-Target Pair