Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50065171 ((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of radiolabeled fibrinogen binding to activated human platelets. | J Med Chem 41: 2492-502 (1998) Article DOI: 10.1021/jm9801096 BindingDB Entry DOI: 10.7270/Q2057F28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50065171 ((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Ability of the compound to inhibit the aggregation of fixed human platelets | J Med Chem 41: 2492-502 (1998) Article DOI: 10.1021/jm9801096 BindingDB Entry DOI: 10.7270/Q2057F28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50065171 ((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of HUVEC adhesion to fibrinogen-coated plates | J Med Chem 41: 2492-502 (1998) Article DOI: 10.1021/jm9801096 BindingDB Entry DOI: 10.7270/Q2057F28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50065171 ((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.65E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of HUVEC adhesion to fibrinogen-coated plates | J Med Chem 41: 2492-502 (1998) Article DOI: 10.1021/jm9801096 BindingDB Entry DOI: 10.7270/Q2057F28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50065171 ((S)-N-((S)-1-Carboxy-2-cyclohexyl-ethyl)-3-{2-[eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.75E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of HUVEC adhesion to fibrinogen-coated plates | J Med Chem 41: 2492-502 (1998) Article DOI: 10.1021/jm9801096 BindingDB Entry DOI: 10.7270/Q2057F28 | |||||||||||
More data for this Ligand-Target Pair |