Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50107402 ((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3) | J Med Chem 46: 5316-25 (2003) Article DOI: 10.1021/jm030146j BindingDB Entry DOI: 10.7270/Q23R0S9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50107402 ((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of a non-peptide radioligand from human recombinant alphaV-beta3 integrin | Bioorg Med Chem Lett 12: 25-9 (2001) BindingDB Entry DOI: 10.7270/Q289171X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50107402 ((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universit£t Marburg Curated by ChEMBL | Assay Description Inhibition of vitronectin binding to human alphaVbeta3 integrin after 2 hrs by ELISA | J Med Chem 57: 5829-34 (2014) Article DOI: 10.1021/jm5004478 BindingDB Entry DOI: 10.7270/Q29W0H3X | |||||||||||
More data for this Ligand-Target Pair |