Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50178241'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178241 (CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...) Show SMILES COc1ccc(cc1F)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H28FN3O3S/c1-32-22-10-8-17(13-21(22)26)18(14-24(30)31)12-20-15-33-23(28-20)6-2-5-19-9-7-16-4-3-11-27-25(16)29-19/h7-10,13,15,18H,2-6,11-12,14H2,1H3,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair