Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50187745 (CHEMBL383412 | c(Arg-Gly-Asp-D-Phe-Val)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of adhesion of K562 cells expressing alphaVbeta3 integrin receptor to vitronectin | J Med Chem 49: 3416-20 (2006) Article DOI: 10.1021/jm060233m BindingDB Entry DOI: 10.7270/Q23X87V0 | |||||||||||
More data for this Ligand-Target Pair |