Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V (Homo sapiens (Human)) | BDBM50265534 (2-((2R,8R,11R,14S)-11-(4-aminobutyl)-8-(3-guanidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Stanford University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]c(RGDyK) form integrin alphaVbeta3 receptor in human U87MG cells | J Med Chem 52: 425-32 (2009) Article DOI: 10.1021/jm801285t BindingDB Entry DOI: 10.7270/Q2Z31ZH1 | |||||||||||
More data for this Ligand-Target Pair |