Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 1 [194-712]' and Ligand = 'BDBM347814'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 1 [194-712] (Homo sapiens (Human))	BDBM347814 (US9790221, Compound 20) Show SMILES Cn1cc(cn1)-c1cccc(c1)-c1ncc(-c2nnc(s2)C(=O)N2CC[C@@H](O)C2)c(NC2CCCNC2)n1 |r| Show InChI InChI=1S/C26H29N9O2S/c1-34-14-18(11-29-34)16-4-2-5-17(10-16)22-28-13-21(23(31-22)30-19-6-3-8-27-12-19)24-32-33-25(38-24)26(37)35-9-7-20(36)15-35/h2,4-5,10-11,13-14,19-20,27,36H,3,6-9,12,15H2,1H3,(H,28,30,31)/t19?,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...				US Patent US9790221 (2017) BindingDB Entry DOI: 10.7270/Q29S1T4F
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