Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM189033'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM189033 (US9169260, 299) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)c1cnn2cccnc12)C1CCCN(Cc2ccncc2)C1 Show InChI InChI=1S/C28H28N8O/c1-20-5-7-23(8-6-20)36-26(32-28(37)24-17-31-35-15-3-11-30-27(24)35)16-25(33-36)22-4-2-14-34(19-22)18-21-9-12-29-13-10-21/h3,5-13,15-17,22H,2,4,14,18-19H2,1H3,(H,32,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	7.2	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...				US Patent US9169260 (2015) BindingDB Entry DOI: 10.7270/Q26H4G6N
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