Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM203531'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM203531 (US9221809, 88) Show SMILES O=c1[nH]c(nc(NC2CCNCC2)c1-c1nc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C20H24N6O2S/c27-18-16(19-23-14-3-1-2-4-15(14)29-19)17(22-13-5-7-21-8-6-13)24-20(25-18)26-9-11-28-12-10-26/h1-4,13,21H,5-12H2,(H2,22,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of IRAK4 (unknown origin) using 5FAM-RKRQGSVRRRVHCCOOH as substrate after 30 mins by IMAP assay				ACS Med Chem Lett 6: 942-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00279 BindingDB Entry DOI: 10.7270/Q26T0PG9
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM203531 (US9221809, 88) Show SMILES O=c1[nH]c(nc(NC2CCNCC2)c1-c1nc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C20H24N6O2S/c27-18-16(19-23-14-3-1-2-4-15(14)29-19)17(22-13-5-7-21-8-6-13)24-20(25-18)26-9-11-28-12-10-26/h1-4,13,21H,5-12H2,(H2,22,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	121	n/a	n/a	n/a	n/a	7.2	25
MERCK SHARP & DOHME CORP. US Patent					Assay Description A 20 ul reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (RP7030, Molecul...				US Patent US9221809 (2015) BindingDB Entry DOI: 10.7270/Q23B5XZM
					More data for this Ligand-Target Pair