Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM303008'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM303008 (US9598440, 149) Show SMILES CO[C@H]1[C@@H](C[C@@H]([C@H]1O)C(C)(C)O)Nc1nc(Nc2cc(C)nc(C)c2)ncc1-c1nc2ccccc2s1 |r| Show InChI InChI=1S/C27H32N6O3S/c1-14-10-16(11-15(2)29-14)30-26-28-13-17(25-32-19-8-6-7-9-21(19)37-25)24(33-26)31-20-12-18(27(3,4)35)22(34)23(20)36-5/h6-11,13,18,20,22-23,34-35H,12H2,1-5H3,(H2,28,29,30,31,33)/t18-,20+,22+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Procedure: A 20 μl reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (R...				US Patent US9598440 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T6V
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