Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM311545'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM311545 (N-(3-carbamoyl-1-pyridin-3- yl-1H-pyrazol-4-yl)-5-...) Show SMILES NC(=O)c1nn(cc1NC(=O)c1cnn2ccc(nc12)N1CCNCC1)-c1cccnc1 Show InChI InChI=1S/C20H20N10O2/c21-18(31)17-15(12-30(27-17)13-2-1-4-23-10-13)25-20(32)14-11-24-29-7-3-16(26-19(14)29)28-8-5-22-6-9-28/h1-4,7,10-12,22H,5-6,8-9H2,(H2,21,31)(H,25,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...				US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J
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