Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM395302'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM395302 (N-{6-(2-Hydroxypropan-2-yl)-2-[3-(trifluoromethoxy...) Show SMILES CC(C)(O)c1cc2nn(CCCOC(F)(F)F)cc2cc1NC(=O)c1cccc(n1)C(F)(F)F Show InChI InChI=1S/C21H20F6N4O3/c1-19(2,33)13-10-15-12(11-31(30-15)7-4-8-34-21(25,26)27)9-16(13)29-18(32)14-5-3-6-17(28-14)20(22,23)24/h3,5-6,9-11,33H,4,7-8H2,1-2H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...				US Patent US10793545 (2020) BindingDB Entry DOI: 10.7270/Q29S1V3D
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM395302 (N-{6-(2-Hydroxypropan-2-yl)-2-[3-(trifluoromethoxy...) Show SMILES CC(C)(O)c1cc2nn(CCCOC(F)(F)F)cc2cc1NC(=O)c1cccc(n1)C(F)(F)F Show InChI InChI=1S/C21H20F6N4O3/c1-19(2,33)13-10-15-12(11-31(30-15)7-4-8-34-21(25,26)27)9-16(13)29-18(32)14-5-3-6-17(28-14)20(22,23)24/h3,5-6,9-11,33H,4,7-8H2,1-2H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...				Bioorg Med Chem Lett 19: 3550-4 (2009) BindingDB Entry DOI: 10.7270/Q2J67K7G
					More data for this Ligand-Target Pair