Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM494075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM494075 (US10988478, Example 120) Show SMILES C[C@]1(CO)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2O1)N1C[C@H]2C[C@@H]1CN2CC(F)(F)F |r| Show InChI InChI=1S/C24H25F3N6O3/c1-23(13-34)8-14-5-18(30-22(35)17-9-29-33-4-2-3-28-21(17)33)19(7-20(14)36-23)32-11-15-6-16(32)10-31(15)12-24(25,26)27/h2-5,7,9,15-16,34H,6,8,10-13H2,1H3,(H,30,35)/t15-,16-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...				US Patent US10988478 (2021) BindingDB Entry DOI: 10.7270/Q2K077DT
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